Nutritional Evaluations


Briefly: Despite its obvious importance nutritional evaluations have only infrequently been done in patients with GI Motility disorders. The approach taken has been to consider some alternative approaches to nutrition in GI motility.

History: The history of work on eating and weight disorders goes back several decades and has focused on both underweight and overweight conditions as well as chemical evaluation of nutritional status.

Projects:  After originally working on classic eating disorders, 35 years ago, an ongoing project has looked at a cohort of obese patients in Memphis for the last 25 years. The later work is still ongoing but nearing completion due to the original goals being met. Not emphasized here is the excellent work the NIH Gastroparesis Research Consortium has been doing as that work is well and appropriately publicized elsewhere. Some ongoing work has focused on patients, both in and out patients, who are dependent for parenteral fluids and/or nutrition for at least some of their nourishment. In addition a related project has dealt with issues of patients with severe developmental disabilities and their struggles to maintain nutrition.

Original Publications, chronologically:

Amarnath RP, Abell TL, Malagelada JRM.  The rumination syndrome in adults. Ann Intern Med. 1986: 105(4):513-518.

Abell TL, Malagelada JRM, Lucas AL, Brown MC, Camilleri M, Go VL, Azpiroz F, Callaway CW,  Kao PC, Zinsmeister AL, Huse D. Gastric electromechanical and neurohormonal function in anorexia nervosa. Gastroenterology. 1987: 93:958-965.

Amarnath RP, Berseth CL, Malagelada JR, Perrault J, Abell TL, Hoffman AD.  Postnatal maturation of small intestinal motility in preterm and term infants. J Gastrointestinal Motility. 1989:1(2); 138-143.

Abell TL, Lou J, Tabbaa M, Batista O, Malinowski S, Al-Juburi A. Gastric electrical stimulation for gastroparesis improves nutritional parameters in short, intermediate and long-term follow-up. J Parenteral and Enteral Nutrition. 2003: 27(4) 277-281.

Kedar A, Nikitina Y, Abell KB, Vedanarayanan V, Griswold ME, Subramony C, Abell TL:  Gastric dysmotility and low serum vitamin D levels in patients with gastroparesis.  Horm Metab Res. 2013 Jan;45(1):47-53. doi: 10.1055/s-0032-1323689. Epub 2012 Sep 6.

Salloum N, Walker MR, Williams PA, Nikitina Y, Helling TS, Abell TL, Lahr CJ, Griffith J.  Evaluation and Treatment of Gastric Stimulator Failure..  Surgical Innovations 2013

(See additional NIH GPCRC articles on similar topics, listed on the Web.)

Review Articles:

Abell, T Malinowski, S, Minocha A. Nutritional Aspects of Gastroparesis and Therapies for Drug-Regractory Patients. NCP 21: 23-33, February 2006.

Abell TL, Minocha A.Gastrointestinal Complications of Bariatric Surgery: Diagnosis and Therapy. Bariatric Surgery. American Journal of the Medical Sciences 331(4): 214-218, April 2006.

Abell TL, Minocha A, Abidi N.Looking to the Future: Electrical Stimulation for Obesity. Bariatric Surgery. American Journal of the Medical Sciences. 331(4): 226-232, April 2006.

Abstracts (numerous—available on request—some new ones below)

Abell KB, Kedar A, Henry OR, Weatherly BB, Sunesara I, Griswold ME, Abell TL.  High serum B12 levels are significantly associated with worsened gastric transit times in patients with DM, but not ID GP

Paine E, Daram S, Taylor M, Pleasant R, Dear T, Nikitina Y, Tang S, Abell T.  Total Parenteral Nutrition at a Tertiary Medical Center: Evaluation of the Ability of a Nutrition Support Team to Predict Duration of TPN. Volume 106, Supplement 2, Oct. 2011, 1145.

Current work: has focused on patients with gut failure who have failed standard therapies and especially those who may respond to GI neurostimulation.


[updated 23 June 2014 by TLAbell]

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